2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine - Names and Identifiers
Name | 2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine
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Synonyms | Didanosine Impurity 10 5-O-ACETYL-2',3'-DIDEOXY-DIDEHYDROINOSINE 5-O-ACETYL-2'',3''-DIDEOXY-DIDEHYDROINOSINE 5-O-Acetyl-2`,3`-dideoxy-2`,3`-didehydroinosine 5-O-Acetyl-2',3'-dideoxy-2',3'-didehydroinosine 2',3'-didehydro-2',3'-dideoxy-5'-acetate inosine 2',3'-Didehydro-2',3'-dideoxy-inosine 5'-acetate 2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine Inosine, 2',3'-didehydro-2',3'-dideoxy-, 5'-acetate
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CAS | 130676-57-2
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2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine - Physico-chemical Properties
Molecular Formula | C12H12N4O4
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Molar Mass | 276.25 |
Density | 1.60 |
2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine - Introduction
5-acetyl -2 ',3'-dideoxydidehydroinosine (abbreviated as 5-AIDDG) is a nucleoside compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 5-AIDDG is a white crystalline solid.
-Melting point: 184-187°C.
-Solubility: Soluble in water and ethanol, insoluble in non-polar solvents.
Use:
- 5-AIDDG is mainly used for nucleic acid biology research and drug synthesis.
-It can be used as an antisense codon nucleotide for artificial synthesis of DNA or RNA.
-It can also be used as an intermediate in drug synthesis.
Preparation Method:
The preparation of 5-AIDDG can be carried out by the following steps:
-First, the sugar moiety at the 3 'end of the nucleotide is synthesized.
-Then, a methylolation reaction is performed to introduce an acetyl group.
-Finally, a deoxygenation dehydrogenation reaction is carried out to obtain the 5-AIDDG product.
Safety Information:
5-AIDDG is generally safe under correct use, but during operation and processing, the following precautions should be paid attention:
-Avoid direct contact with skin and eyes.
-Pay attention to good ventilation conditions during use.
-Use personal protective equipment, such as lab gloves and goggles.
-should be stored in a sealed, cool, dry place, away from fire and oxidant.
Last Update:2024-04-09 21:01:54